About Short-Term Scientific Missions:
EURO-CHOLANGIO-NET (European Cholangiocarcinoma Network) is actively seeking investigators to take part in short-term scientific missions (STSMs) in COST Action member countries or at approved institutions. STSMs are training initiatives that have a minimum duration of at least 5 days (including travel). The aims of STSMs are to promote collaboration and exchanges between participating institutions by providing investigators with the opportunity to visit institutions of scientific excellence in order to learn techniques or expertise that may be lacking at the local institution.
Successful applicants will receive a STSM grant to be applied towards their overall travel, accommodation, and meal expenses according to the following scheme:
- Up to a maximum of EUR 3 500 in total can be afforded to each successful applicant;
- Up to a maximum of EUR 160 per day can be afforded for accommodation and meal expenses.
What we are looking for:
We are seeking investigators to take part in short-term scientific missions. STSM applicants must be engaged in an official research programme as a PhD student or postdoctoral fellow or can be employed by, or affiliated to, an institution, organisation, or legal entity which has within its remit a clear association with performing research.
We invite interested investigators to submit their proposals that address how we can achieve the objectives of our Action, with particular reference to the development and dissemination of registries and the main working group projects. Proposals will be selected on the basis of scientific excellence, young researcher participation, gender equality, geographical inclusiveness, and inclusiveness target country involvement.
Please refer to the Memorandum of Understanding on our website for more information about our Action, deliverable objectives, implementation strategies, and working groups: https://www.cost.eu/actions/CA18122/#downloads
Please refer to Section 8 of our Vademecum for more information on STSM eligibility: https://www.cost.eu/wp-content/uploads/2019/07/Vademecum_June2019.pdf
How to apply:
Interested candidates can apply by submitting a motivation and workplan summary of approximately 2000 words which includes:
1. Aim & motivation – Please explain the scientific and/or other motivation for the STSM and what scientific and/or other outcomes you aim to accomplish with the STSM.
2. Proposed contribution to the scientific objectives of the Action.
3. Techniques – Please detail what techniques or equipment you may learn to use, if applicable.
4. Planning – Please detail the steps you will take to achieve your proposed aim.
Candidates must submit their STSM applications online at the following web address: https://e-services.cost.eu/stsm
For more information please contact firstname.lastname@example.org
Select opportunities currently available:
Institute: Department of Experimental and Clinical Medicine, Florence, Italy
Training opportunity/area of research: metabolics aspect of cholangiocarcinoma stem-like compartment, stemness features and cholangiocarcinoma associated stroma
Institute: Wolfson Wohl Cancer Research Centre, Glasgow, U.K.
Contact email: email@example.com
Training opportunity/area of research: Dr. Braconi’s research team integrates the study of molecular biology with clinical research to sustain a patient-oriented programme in biliary cancers. She combines the study of transcriptional and post-transcriptional modifications with patient derived organoids to inform drug discovery and biomarker development in cholangiocarcinoma. Dr. Braconi is also leading the Biliary Cancer Clinic at the Beatson West of Scotland Cancer Centre and is glad to provide training opportunities for clinical trainees with a focussed interest in cholangiocarcinoma.
Institute: Biodonostia Health Research Institute, San Sebastián, Gipuzkoa, Spain
Training opportunity/area of research: biomarkers, pathobiology, experimental therapeutics, NAFLD & cirrhosis-related CCA, epidemiology, clinical (oncology & surgery).
Institute: Centre for Functional Genomics and Bio-Chips, Institute of Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
Training opportunity/area of research: Our group uses omics and systems medicine tools to study liver metabolic diseases and primary liver cancers. Our focus is on understanding the role of different factors, such as cholesterol (intermediates and metabolites), circRNA and disruptions of circadian rhythm, in the progression of liver diseases with a special focus on gender bias. We work with patients’ samples, animal models and cell lines. We are open to collaborations and offer training and collaboration in basic medicine for: (1) Transcriptome analyses using Nanopore long-read sequencing; (2) Circadian experiments in cell lines, testing how different factors affect the circadian rhythm; (3) Measuring the expression of circRNA in samples and perform functional analyses of circRNA in cell lines.
Institute: The Research Institute for Medicines (iMed.ULisboa) & Faculty of Pharmacy, Universidade de Lisboa, Lisbon, Portugal
Training opportunity/area of research: biochemical, molecular and cellular tools for dissecting the role of microRNAs in liver pathophysiology. At the moment, we are focusing on the role of microRNAs and extracellular vesicles (EVs) in inter-organ communication in the setting of NAFLD and liver cancer; as well as its exploitation for the diagnosis, treatment, monitoring and prevention of liver disease.
Institute: Dipartimento di chimica e tecnologie del farmaco, Faculty of Pharmacy and Medicine, Sapienza University of Rome, Rome, Italy
Contact email: Bruno.Botta@uniroma1.it
Professor Bruno Botta’s Unit has expertise in developing chemical libraries of novel bioactive compounds (variably substituted flavonoids, benzophenones, xanthones, anthraquinones, alkaloids, steroids, terpenoids), many identified from natural extracts obtained from medicinal plants. The Unit can provide expertise with a unique in‐house library of about one thousand bioactive natural compounds, mostly isolated from several plants used in traditional medicine of South America and collected over the years. Botta’s group will be able to develop structure-based and ligand-based drug design approaches for selecting a limited number of candidate molecules likely to be active against a chosen biological receptor. In addition, Professor Bruno Botta’s Unit has expertise in another important phase of drug discovery: optimizing active Hits up to Lead compounds or, at least, Lead candidates by improving potency, stability, physicochemical features (i.e. water solubility, logP, polar surface area PSA, etc.), chemical properties, and metabolic/pharmacokinetics parameters (click here for more info).